一个管理访问协议的利拉格卢提德的体重管理:在爱尔兰的一个回顾性,观察性研究
Rosealeen Barrett1, Amelia Smith1, Claire Gorry1
1Medicines Management Programme, Health Services Executive, Dublin, Ireland; Department of Pharmacology and Therapeutics, School of Medicine, Trinity College Dublin, Ireland.
爱尔兰的一项管理访问协议 (MAP) 改善了针对特定患者群体的体重管理用利拉格卢提德的获取,证明了成本效益和可控支出.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 临床实践 临床实践
背景情况:
- 利拉格卢提德 (萨克森达) 显示在体重管理中有效,但其在爱尔兰的成本效益尚未被证明.
- 高成本药物需要谨慎管理,以确保医疗保健系统的价值.
研究的目的:
- 评估管理访问协议 (MAP) 在促进真实世界的liraglutide访问中的作用.
- 评估爱尔兰特定患者亚群中的利拉格卢提德的成本效益和支出控制.
主要方法:
- 分析国家MAP数据库和药房对liraglutide应用的声明.
- 已批准的MAP应用程序与关键试验数据和未批准的应用程序的比较.
- 与没有MAP的预测场景相比,利用和支出的评估.
主要成果:
- 在第一年,根据MAP的7927个liraglutide申请中,52.2%被批准.
- 经批准的患者在关键特征 (年龄,HbA1c,BMI) 方面与关键试验子组和未经批准的病例有所不同.
- 支出为310万欧元,如果所有申请都获得批准,可能节省高达240万欧元.
结论:
- 马普成功地为一个子群体提供了利拉格卢提德的获取机会.
- 根据卫生技术评估,这种方法可以确保患者在利拉格卢提德有效且具有成本效益的情况下获得治疗.
- 实际上,MAP包含了这一高预算药物的总体支出.
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