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制造Necator americanus作为一种传染性挑战剂:加速人类虫疫苗开发

Guacyara Erwin1, Larissa Scholte1, Rafaela Saes1

  • 1Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, The George Washington University, Washington, DC, 20052, United States of America.

Microbial pathogenesis
|April 17, 2025
PubMed
概括

该研究详细介绍了用于疫苗挑战模型的传染性虫幼虫 (NaL3) 的cGMP生产情况. 这确保了N. americanus Glutathione-S-Transferase-1 (Na-GST-1) 人类虫候选疫苗的安全性和有效性测试.

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