中等度Zr-Nb-Ti-O合金用于骨植入物的弹性应变和强度延长性能
Zhaolin Hua1, Dechuang Zhang1, Lin Guo1
1School of Materials Science and Engineering, Xiangtan University, Xiangtan 411105, China.
Acta biomaterialia
|April 17, 2025
概括
添加氧气可以增强贝塔型Zr-Nb-Ti (ZNT) 中等合金 (MEAs) 用于骨科植入物. ZNTO MEAs表现出更好的强度,柔性和耐腐蚀性,显示出临床应用的潜力.
科学领域:
- 材料科学 材料科学 材料科学
- 生物材料工程 生物材料工程
- 金工业是金工业的一个方面.
背景情况:
- 贝塔型Zr-Nb-Ti (ZNT) 中等合金 (MEAs) 由于其机械性能,耐腐蚀性和生物相容性,对骨科植入物具有前景.
- 为了提高ZNT MEAs的临床性能,需要进一步改进弹性允许应变,强度和柔性.
研究的目的:
- 研究氧气添加对ZNT MEAs微观结构,机械性能,耐磨性和耐腐蚀性以及生物相容性的影响.
- 评估含氧ZNT MEAs (ZNTOx) 作为先进的骨科植入物材料的潜力.
主要方法:
- 制造 (ZrNbTi) 100-xOx (x = 0, 0.5, 1.0, 1.5) MEAs使用弧,然后冷和回火.
- 使用MG-63细胞对微结构,机械性能 (弹性允许应变,强度,延伸),耐磨性和耐腐蚀性以及体外生物相容性的系统性表征.
主要成果:
- 添加氧气显著增强强度和柔性通过间歇性固体溶液强化和应变硬化.
- 与ZNT0 (没有氧气) 相比,ZNTOx MEAs显示了更好的弹性允许应变和强度延长产品.
- ZNTO1.5表现出最佳的性能: ~1.5%的允许应变, ~1150 MPa的最终强度和 ~22%的延伸. 耐磨性和耐腐蚀性随氧含量增加而增加,性能优于Ti-6Al-4V和Co-Cr-Mo合金.
- ZNTOx MEAs与MG-63细胞显示出极好的生物相容性 (活力>97%).
结论:
- 氧是一种有效的合金元素,可以增强ZNT MEAs在骨科应用中的综合性质.
- 由于其优越的机械性能,耐磨性和耐腐蚀性以及生物相容性,ZNTO1.5 MEA显示出作为骨科植入物材料的巨大潜力.
- 这些发现支持开发先进的ZNTOx MEAs,用于苛刻的生物医学应用.
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