少数民族和可修改的痴呆风险:对基于英国的证据进行范围审查
Magda Jordão1,2, Lin Gong3,2, Deirdre Andre4
1Academic Unit for Ageing and Stroke Research, University of Leeds, Leeds, UK m.i.jordao@leedsbeckett.ac.uk.
Journal of epidemiology and community health
|April 17, 2025
概括
少数民族面临更高的痴呆风险. 目前英国关于痴呆风险因素的研究往往排除了这些因素,缺乏针对个性化预防策略的具体数据和一致的方法.
科学领域:
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
- 社会学 社会学 社会学
背景情况:
- 少数族裔群体的痴呆症负担不成比例地高.
- 在一般人群中,通过12个可修改的风险因素 (MRF),痴呆风险可以降低高达40%.
- 现有的痴呆症MRF研究在英国没有系统地包括少数民族.
研究的目的:
- 进行范围审查,绘制少数民族在英国痴呆症MRF研究中的纳入情况.
- 确定在涉及这些群体的研究中使用的可修改风险因素 (MRF) 和研究方法.
主要方法:
- 在多个数据库 (Medline,Embase,PsycInfo,Web of Science,CINAHL) 和灰色文学中进行了全面的文献搜索.
- 符合条件的研究分析了12个MRF中的一个或多个与少数族裔群体中痴呆相关的MRF.
- 数据提取工具以患者和公众参与为基础,使用频率和图形描述数据.
主要成果:
- 在7748个选记录中,包括了14项研究,主要使用广泛的种族分类.
- 高血压,糖尿病和抑郁症是最常被研究的MRF,而社会接触和空气污染是最少被研究的.
- 报告指出,MRF测量不一致,缺乏种族特异性数据报告,缺乏对MRF相互作用的研究.
结论:
- 迫切需要更多的研究,重点关注特定的种族群体,采用一致的措施.
- 未来的研究应该调查MRF的相互作用,包括歧视,以实现个性化降低风险.
- 这种方法对于为不同社区制定有效的痴呆症预防策略至关重要.
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