增强抗生素管理计划对四家泰国医院抗生素管理的影响
Joint Commission journal on quality and patient safety
|April 17, 2025
概括
泰国的增强抗菌管理计划 (ASP) 网络改善了抗生素使用的适当性和减少了消费. 这种协作方法显示出对抗亚洲医院抗菌素耐药性的承诺.
科学领域:
- 医疗保健管理健康管理
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗微生物药物管理计划 (ASP) 对于优化抗微生物药物使用和打击耐药性至关重要.
- 关于在亚洲医疗保健环境中加强ASP网络实施的数据有限.
研究的目的:
- 评估泰国增强的ASP协作网络的有效性.
- 评估抗生素消费,适当性和多药耐药生物体 (MDRO) 发病率的改善.
主要方法:
- 在四个不同的泰国医院 (2021-2022) 进行了一项准实验性研究.
- 通过差距分析评估基准ASP活动.
- 测量了抗生素消耗 (DDD/1000个患者日),使用适当性和MDRO发生率.
主要成果:
- 适当使用抗生素的显著增加 (86.5% vs 74.4%,p < 0.05).
- 在所有参与医院减少目标抗生素消费.
- 在一家医院,抗卡巴因的*Acinetobacter baumannii*和MRSA发病率显著下降;整体MDRO病原体发病率在两家医院下降.
结论:
- 增强的ASP网络成功地改善了ASP在各种泰国医院环境中的实施.
- 解决了诸如财政支持,提高抗生素使用适当性和减少消费等挑战.
- 证明了减少多抗药性病原体的潜力,突出显示了亚洲协作ASP网络的价值.
更多相关视频
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
1.1K
12:58A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
Published on: May 25, 2017
8.9K
相关概念视频
Combined Effects of Drugs: Synergism
3.6K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.6K
Healthcare Associated Infections II: Preventive Measures
2.3K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.3K
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
272
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
272
Antibiotic Selection
51.9K
Overview
51.9K
Pulmonary Tuberculosis V
150
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
150
