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来自Lobophytum crassum的20-乙氨二醇乙 (ASB) 通过IGF1R/PI3K/AKT/mTOR通路在体外表现出抗癌活性

Yuanmin Chang1,2, Shoumao Shen3,4, Liting Zhang2

  • 1Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Chemistry & biodiversity
|April 17, 2025
PubMed
概括

从海洋珊瑚中提取的20-乙氨醇乙基 (ASB) 显示出对非小细胞肺癌 (NSCLC) 治疗的前景. 通过向IGF1R途径,ASB有效地抑制NSCLC细胞生长,诱导细胞亡,并减少转移.

关键词:
20 - 乙二烯基单元化物 B.灭症 (apoptosis) 是一种死亡的过程.表皮介酶过渡 (EMT) 发生.海洋天然产品海洋自然产品网络药理学 网络药理学非小细胞肺癌 (NSCLC) 是一种非小细胞肺癌.

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