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Updated: May 11, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
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RNase1驱动的ALK激活是非小细胞肺癌中的瘤原驱动因素和治疗标

Zhengyu Zha1, Chunxiao Liu2, Meisi Yan3

  • 1Department of Thoracic Surgery and Institute of Thoracic Oncology, West China Hospital, University of Sichuan, Chengdu, Sichuan, China.

Signal transduction and targeted therapy
|April 17, 2025
PubMed
概括

人体分泌核糖酶1 (RNase1) 在肺癌中激活野生型ALK,产生RNase1驱动的ALK激活 (RDAA). 这种RDAA是非小细胞肺癌 (NSCLC) 治疗的新标,与ALK抑制剂显示出希望.

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