肺癌的营养风险,功能衰退和症状负担:基于PG-SGA得分和生物化学数据的研究
Shasha Shen1,2, Shiyun Xing1,2, Tingting Shen3
1Department of Head and Neck Oncology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Frontiers in nutrition
|April 18, 2025
概括
营养状况不佳显著恶化肺癌患者的生活质量. 早期的营养干预对于改善患者的结果和缓解症状至关重要.
科学领域:
- 在瘤学瘤学.
- 临床营养学 临床营养学
- 生活质量研究 研究 生命质量研究
背景情况:
- 肺癌显著影响患者的营养状况和生活质量 (QOL).
- 评估营养状况对于有效的患者管理和支持性护理至关重要.
研究的目的:
- 研究肺癌患者的营养状况和QOL之间的关系.
- 分析营养支持的临床应用及其与生化标志物和身体功能的关联.
主要方法:
- 270名住院肺癌患者的营养状况使用PG-SGA和NRS-2002进行了评估.
- 使用EORTC QLQ-C30问卷来评估生活质量.
- 分析了营养状况,生化标志物,身体成分和QOL之间的相关性.
主要成果:
- 38.89%的患者具有高营养风险 (PG-SGA ≥9),其中77.04%没有获得营养支持.
- 较高的PG-SGA分数与较差的身体,角色,情绪和社会功能相关.
- PG-SGA得分与生化标志物和增加的症状负担 (疲劳,恶心,疼痛) 有显著的关联.
结论:
- 营养状况是肺癌患者QOL的重要决定因素.
- PG-SGA分数有效地反映了功能能力和症状负担.
- 改善营养干预可以提高功能状态和生活质量,特别是在高风险患者中.
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