移植后的饮食指南:这是恢复和移植存活的缺失环节吗?
Suzanne Schneider1, Deborah Biggerstaff1, Thomas M Barber2,3
1Directorate Applied Health, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
概括
优化营养摄入可以通过减轻缺血再输液损伤 (IRI) 和氧化应激来改善移植恢复和移植存活率. 本综述强调了支持移植后代谢健康的关键营养素.
科学领域:
- 移植免疫学 移植免疫学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
背景情况:
- 脏移植生理学受到器官采购的影响.
- 由缺氧和氧化应激驱动的缺血再输液损伤 (IRI) 会增加移植并发症.
- 营养支持和抗氧化剂在改善移植存活方面表现有前途.
研究的目的:
- 审查宏观和微量营养素对脏全移植恢复和存活的影响.
- 在外科手术期间和移植后长达一年的时间内优化代谢环境.
- 为了解决医疗营养治疗指南缺乏对脏移植接受者.
主要方法:
- 对当前文学和灰色文学进行叙事审查.
- 专注于外科手术前期至移植后的一年.
- 分析特定的宏观和微量营养素对所有移植结果的影响.
主要成果:
- 营养干预可以减轻IRI和氧化应激.
- 特定的营养素可以改善细胞的能量供应,并提高长期的移植存活率.
- 患有先前存在的营养缺乏症的患者可能会显著受益.
结论:
- 优化营养摄入对于移植的恢复和生存至关重要.
- 需要进一步的研究,以建立基于证据的营养治疗指南.
- 有针对性的营养策略可以减轻与移植相关的损伤并改善结果.
相关概念视频
Renal Failure: Dose Adjustments
35
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
35
Kidney Structure
66.8K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
66.8K
Appendicitis-II: Diagnostic Studies and Management
47
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
47
Factors Affecting Renal Clearance: Renal Impairment
30
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
30
Dialysis
228
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
228


