对商业质子束疗法系统的圆束计算机断层扫描重建
Josh W H Lindsay1,2, Simon J P Meara3,1, Matthew Clarke3
1Division of Cancer Sciences, The University of Manchester, Manchester, UK.
Physics and imaging in radiation oncology
|April 18, 2025
概括
一个新的离线工作流可以重建用于质子疗法的束计算机断层扫描 (CBCT) 图像,减少文物并改善图像质量以提高辐射治疗的准确性.
科学领域:
- 医学物理 医学物理
- 放射治疗技术 放射治疗技术
- 图像重建 图像的重建
背景情况:
- 圆束计算机断层扫描 (CBCT) 对于图像导向放射治疗至关重要,它可以跟踪解剖变化和精确的患者设置.
- 精确的CBCT图像重建对于优化质子束治疗中的辐射输送至关重要.
- 现有的离线重建方法是系统特定的,通常需要适应新型成像系统.
研究的目的:
- 为商用质子束疗法机器开发和验证一个离线方法来从2D投影数据中重建CBCT图像.
- 为了考虑在CBCT获取过程中门架旋转引起的曝光和梁硬化变化的变化.
- 为优化获取参数提供一个工具,并为质子疗法 (CBCT) 开发新的重建过程.
主要方法:
- 从固体水幽灵获得的投影数据,以建模蝶结波器运动和光束硬化.
- 利用Catphan504幻影数据和系统CBCT重建用于方法验证.
- 通过统一性,信号与噪声比率 (SNR) 和对比与噪声比率 (CNR) 的指标对比临床重建来评估工作流的性能.
主要成果:
- 开发的离线工作流有效地消除了幻影和患者图像中的新月器件,这些是由于可变曝光和光束硬化引起的.
- 重建的图像显示了与临床系统重建相比的信号与噪声和对比度与噪声的比率.
- 观察到图像质量指标的微小差异,并归因于蝶结波器内的潜在相互作用效应.
结论:
- 一个有效的离线CBCT重建工作流已经成功地为商业质子疗法系统开发.
- 这个工作流作为优化CBCT获取参数和探索新型重建技术的宝贵工具.
- 该方法通过提高图像质量和减少文物来增强CBCT在质子疗法的实用性.
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