揭开碳水化合物消化不良的奥秘:临床综述
Brooks D Cash1, Daksesh Patel2, Kate Scarlata3
1Gastroenterology, Hepatology, and Nutrition, UT Health Science Center at Houston, McGovern Medical School, Houston, Texas, USA.
The American journal of gastroenterology
|April 18, 2025
概括
碳水化合物不耐受,经常被忽视,导致无法解释的胃肠道问题. 通过饮食和酶疗法识别和管理消化不良,可以显著改善受影响患者的症状.
科学领域:
- 胃肠病学 胃肠病学
- 消化系统健康 消化系统健康
- 肠-大脑相互作用
背景情况:
- 碳水化合物不耐受是导致无法解释的胃肠道症状的常见原因,特别是在肠-大脑相互作用障碍的患者中.
- 症状源于未吸收的碳水化合物的细菌发酵,增加了肠道中的气体和透负荷.
- 这种机制影响各种碳水化合物,如乳糖,果糖和FODMAP (可发酵的寡糖,分糖,单糖和多醇).
研究的目的:
- 探索碳水化合物不耐受是胃肠道症状的原因.
- 讨论对碳水化合物消化不良的诊断方法和管理策略.
- 突出饮食修改和酶替代疗法的作用.
主要方法:
- 对碳水化合物不耐受和消化不良的机制的审查.
- 讨论诊断工具,包括病史,呼吸测试和酶测试.
- 强调饮食修改和酶替代疗法.
主要成果:
- 碳水化合物消化不良可能是主要的 (遗传酶缺陷) 或次要的 (获得的胰腺/小肠损伤).
- 确认分糖酶缺乏症需要临床相关性.
- 饮食修改是主要的治疗方法,旨在通过尽可能自由的饮食控制症状.
结论:
- 识别碳水化合物消化不良的患者对于管理无法解释的胃肠道症状至关重要.
- 对于复杂的病例,建议采用涉及营养学家的多学科方法.
- 酶替代疗法,如圣酶,可以帮助饮食管理和缓解症状.
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