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Updated: May 11, 2025

Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy
10:09

Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy

Published on: April 28, 2011

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通过溶剂中的相互作用能量网络研究蛋白质热稳定性和折叠率

Jun Liao1, Mincong Wu1, Fanjun Meng1

  • 1Institute of Biophysics, School of Physics, Huazhong University of Science and Technology, Wuhan, China.

Journal of computational chemistry
|April 18, 2025
PubMed
概括

蛋白质残留相互作用能量网络准确地预测蛋白质折叠率,稳定性和全性通路. 这种以能量为基础的方法,由GPU加速,比以距离为基础的方法更准确地了解蛋白质特征.

关键词:
异质性通路的异质性通路互动能源网络互动能源网络蛋白质折叠率是多少 蛋白质折叠率是多少蛋白质的热稳定性 热稳定性

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Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

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Measuring Biomolecular DSC Profiles with Thermolabile Ligands to Rapidly Characterize Folding and Binding Interactions09:15

Measuring Biomolecular DSC Profiles with Thermolabile Ligands to Rapidly Characterize Folding and Binding Interactions

Published on: November 21, 2017

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Protein Folding

Overview
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Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
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Noncovalent Attractions in Biomolecules

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Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
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Protein-protein Interfaces02:04

Protein-protein Interfaces

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Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
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