产前环境烟草烟雾暴露与早产之间的关联:系统性审查和元分析
Tong-Tong Fu1, Han-Xiao Luo1, Zhi-Jing Na2
1Department of Nursing, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Acta obstetricia et gynecologica Scandinavica
|April 18, 2025
概括
暴露在二手烟中显著增加了21%的早产风险. 这一系统审查强调了被动吸烟对怀孕结果的持续影响,强调了需要进行公共卫生干预的必要性.
科学领域:
- 公共卫生 公共卫生
- 产科和妇科 产科和妇科
- 环境健康 环境健康
背景情况:
- 被动吸烟,或暴露于环境烟草烟雾 (ETS),仍然是一个全球性的健康问题.
- 以前的研究表明,ETS暴露和不良妊娠结果之间存在联系.
- 在最近的吸烟禁令背景下,ETS对早产率的影响需要进行更新的评估.
研究的目的:
- 系统地审查和元分析与被动吸烟相关的全球早产风险.
- 评估ETS对早产率的持续影响.
- 评估在实施更严格的禁烟令后风险的潜在变化.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在主要数据库 (PubMed,Embase,CINAHL,Web of Science) 进行全面的文献搜索,截至2024年2月.
- 包括符合条件的观察性研究与使用概率比率 (OR) 和异质性评估 (I2) 的统计分析 (I2).
主要成果:
- 在暴露于环境烟草烟雾 (ETS) 的妇女中,早产的几率增加了21% (OR,1.21;95% CI,1.10-1.32).
- 发现了显著的异质性 (I2 = 76.2%),在队列/横截面研究,亚洲人群,更大的样本大小和最近的出版物中存在更强烈的关联.
- 结果表明,在各种敏感性和子组分析中,结果具有稳定性.
结论:
- 产前暴露于环境烟草烟雾是早产的重要危险因素.
- 有效的公共卫生干预措施,包括无烟政策和宣传活动至关重要.
- 减少ETS暴露对于改善母亲和婴儿健康结果至关重要.
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