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Updated: May 11, 2025

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
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氨基化物通道BEST1是由细胞外GABA激活的

Swati Pant1,2, Stephanie W Tam1,3, Stephen B Long1

  • 1Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.

Proceedings of the National Academy of Sciences of the United States of America
|April 18, 2025
PubMed
概括

贝斯特罗芬-1 (BEST1) 是一种化物通道,由神经递质胺酸 (GABA) 直接激活. 这一发现揭示了GABA信号传递和BEST1通道调节的新机制.

关键词:
对于GABA来说,这是一个很好的选择.激活方式 激活方式贝斯特罗芬 (bestrophin) 是一种蛋白质.化物道化物道接收器 接收器 接收器接收器

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