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Updated: May 11, 2025

In Vitro Transcribed RNA-based Luciferase Reporter Assay to Study Translation Regulation in Poxvirus-infected Cells
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在阿尔法病毒中,一个保存的光终结子优化了蛋白质生产和加工之间取决于温度的权衡

Tamanash Bhattacharya1, Eva M Alleman1, Tiia S Freeman1

  • 1Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.

Science advances
|April 18, 2025
PubMed
概括

像Sindbis病毒 (SINV) 这样的双宿主阿尔法病毒使用欧帕尔密码子来有效复制. 温度会影响子的性能,SINV突变可以在较低的温度下恢复感觉子的功能.

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