虚拟现实认知训练对执行功能和前性记忆在帕金森病和健康衰老中的影响
Eleonora Fiorenzato1, Silvia Zabberoni2, Maria Stefania De Simone2
1Parkinson and Movement Disorders Unit, Study Center for Neurodegeneration (CESNE), Department of Neuroscience, University of Padua, Via Giustiniani, 5 - 35128 Padua, Italy; Department of General Psychology, University of Padua, Via Venezia, 8 - 35131 Padua, Italy; Padua Neuroscience Center (PNC), University of Padua, Via Giuseppe Orus, 2/B, 35129 Padua, Italy.
Journal of the neurological sciences
|April 18, 2025
概括
沉浸式虚拟现实认知训练在帕金森病患者中改善了前性记忆和执行功能. 这种新的方法也提高了健康的老年人规划能力.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 老年学是指老年学的学科.
背景情况:
- 帕金森病 (PD) 经常导致神经认知障碍,影响日常生活.
- 轻度认知障碍 (PD-MCI) 是一种常见的亚型,影响执行功能 (EF) 和潜在记忆 (PM).
- 需要新的干预措施来解决PD和老龄化人口的认知衰退.
研究的目的:
- 评估沉浸式虚拟现实 (iVR) 认知训练 (CT) 的有效性,以改善PD-MCI中的EF和PM.
- 检查健康老年人 (HC) 中EF培训的潜在转移效应.
- 评估认知改进的长期可持续性.
主要方法:
- 一个双盲随机受控试验,涉及30名PD-MCI和30名HC参与者.
- 参与者被分配到一个为期4周的EF培训或活性安慰剂组,通过远程医疗和iVR提供.
- 认知表现在干预前,干预后和2个月后期进行了评估.
主要成果:
- 接受EF培训的PD-MCI组显示了PM和EF (特别是抑制) 的显著改善,持续在2个月内.
- 在PD-MCI中的PM增强与改善的抑制和转移能力有关.
- 在EF培训组中,健康的老年人表现出更好的规划能力,这在随访中也持续了下去.
结论:
- 基于iVR的EF培训是一种有效的非药物干预,用于提高PD-MCI和HC的认知能力.
- 培训显示了前性记忆和执行功能的显著改善.
- iVR和远程医疗为各种人群提供可访问,个性化的认知干预.
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