额头 - 听觉皮层相互作用和感官预测在marmoset子的声乐生产期间
Joji Tsunada1, Steven J Eliades2
1Beijing Institute for Brain Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 102206, China; Chinese Institute for Brain Research, Beijing 102206, China; Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka 0208550, Iwate, Japan.
Current biology : CB
|April 18, 2025
概括
前额皮层 (FC) 区域在发声之前向听觉皮层 (AC) 发送预测信号,帮助语音控制. 改变反时的双向通信表明声调整的错误检测.
科学领域:
- 神经科学是一个神经科学.
- 审计处理 审计处理
- 语音制作 语音制作
背景情况:
- 语音控制依赖于预期和实际语音输出之间的错误计算.
- 听觉皮层 (AC) 在发声时被抑制,但对听觉反差异敏感.
- 从前额皮层 (FC) 区域的自上而下的信号被假设是导致这种AC抑制的.
研究的目的:
- 调查FC是否是发声期间AC预测和抑制信号的来源.
- 探索声控和听觉前额交互的基础的神经机制.
主要方法:
- 在自发发起的发声过程中,马尔莫塞特子的AC和FC同时进行神经记录.
- 分析多单元活动和达频段功率.
- 格兰杰因果关系分析以评估FC和AC之间的定向信号.
主要成果:
- 在早期声声前期 (发声前1到0.5秒) 中,AC和FC的神经活动增加.
- 在这个前声期,FC向AC显示了指向信号.
- 声前活动与交流抑制和发声声学相关 (例如基本频率).
- 在改变的听觉反过程中观察到双向的听觉前额相互作用,预测声乐补偿.
结论:
- 在发声过程中,FC与AC通信,传输感官预测信息.
- 发声期间的双向信号表明声控错误检测中的作用.
- 这些发现阐明了语音产生的听觉前额交互的神经基础.
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