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通过多omics分析,二氧化纳米颗粒诱导的肝毒性的主要毒性途径

Jiaqi Shi1, Ying Ma1, Nairui Yu1

  • 1Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing, 100191, People's Republic of China; Beijing Key Laboratory of Toxicological Research and Risk Assessment for Food Safety, School of Public Health, Peking University, Beijing, 100191, People's Republic of China.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
|April 18, 2025
PubMed
概括

二氧化纳米颗粒 (TiO2 NPs) 通过改变关键代谢途径,导致肝毒性. 这项研究使用了多组学来揭示这些TiO2 NP毒性机制在老鼠和人类细胞.

关键词:
肝细胞 肝细胞 肝细胞代谢学 代谢学 代谢学蛋白质组学是指蛋白质组学.二氧化纳米颗粒的二氧化.

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