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Updated: Jun 14, 2025

Model of Ischemic Heart Disease and Video-Based Comparison of Cardiomyocyte Contraction Using hiPSC-Derived Cardiomyocytes
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Published on: May 5, 2020

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遗传性心肌病的hiPSC模型中的特征和药理反应性

Merel Gerritse1, Willem B van Ham2, Chris Denning3

  • 1Utrecht Regenerative Medicine Center, Circulatory Health Research Center, University Utrecht, 3584 CS Utrecht, the Netherlands; Department of Medical Physiology, Division Heart & Lungs, University Medical Center Utrecht, 3584 CM Utrecht, the Netherlands.

Pharmacology & therapeutics
|April 18, 2025
PubMed
概括

遗传性心肌病,心力衰竭的主要原因,共享的细胞缺陷,尽管不同的遗传起源. 人类诱导的多能干细胞衍生心肌细胞 (hiPSC-CMs) 揭示了这些共同的表型和潜在的治疗策略.

关键词:
节律失常性心肌病变症 节律失常性心肌病变症扩展性心肌病变异性疾病疾病建模 疾病建模过度缩性心肌病变的情况.在体外 (in vitro) 的情况下.遗传性心肌病变性是一种遗传性心肌病变性.这就是hiPSC-CMs.

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