在运动期间验证磁共振成像衍生的静脉氧和和氧消耗测量
Rachel J Skow1, Stephen J Foulkes1,2, Hendrik Mugele3
1Integrative Cardiovascular Exercise Physiology and Rehabilitation Lab, Faculty of Nursing, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
概括
这项研究验证了一种新的非侵入性MRI方法,用于测量运动期间静脉氧和度. 该技术准确评估氧气消耗及其决定因素,为血液采样提供可靠的替代方案.
科学领域:
- 身体生理学 身体生理学
- 医疗成像医学成像
- 运动科学 运动科学
背景情况:
- 精确测量静脉氧和度对于了解氧耗和Fick决定因素至关重要.
- 目前的方法通常涉及侵入性血液采样,限制了运动期间的持续或广泛监测.
研究的目的:
- 评估一种新的磁共振成像 (MRI) 方法的有效性和可靠性,即基于悬浮计的氧度计 (SBO),用于在运动期间非侵入性测量静脉氧和度.
- 使用Fick方法与参考措施相比,评估MRI衍生的氧气消耗 (V·o2) 的准确性.
主要方法:
- 使用SBO和便携式血液分析仪 (iSTAT) 测量了静脉氧和,在休息和手握运动中对成年人进行测量.
- 氧气消耗 (V·o2) 用MRI衍生的Fick决定因素 (包括静脉氧和和心脏MRI的心脏输出SBO) 确定,并与间接热量计在增量运动期间比较.
主要成果:
- 在手臂运动期间静脉氧和度的SBO和iSTAT测量之间发现了良好的到优秀的一致性 (ICC:0.86).
- 对于iSTAT (ICC:0.97) 和SBO (ICC:0.90) 测量,测试重复测试的可靠性都非常出色.
- 通过MRI-Fick获得的V·o2与肺V·o2测量结果有很好的一致性 (ICC:0.98).
结论:
- 静脉氧和度的非侵入性MRI-SBO测量可靠,并且与运动期间直接取血样有很强的一致性.
- 基于MRI的Fick方法准确地确定了氧气消耗,验证了这种技术对各种运动强度的氧气吸收及其决定因素的非侵入性评估.
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