腹部和同时发生的胸部HIPEC,称为HITAC:技术和术后课程
Dahbia Djelil1, Ulrich Clarac2, Daniel Eyrauld2
1Université Paris Cité, UMR 1275 : CAP Paris Tech, 75010 Paris, France; Surgical department of Hepato-Biliary-Pancreatic Gastrointestinal Surgery and Liver Transplantation, Pitié-Salpêtrière Hospital AP-HP, Paris, France.
Journal of visceral surgery
|April 18, 2025
概括
细胞还原性手术与高温腹腔内化疗 (HIPEC) 和胸内化疗 (HITAC) 是可行的膜参与的癌症. 这种综合方法显示,对低度腹膜间皮瘤的长期结果是有利的.
科学领域:
- 手术瘤学手术瘤学
- 胃肠道瘤学 胃肠道瘤学
- 胸部瘤学 胸部瘤学
背景情况:
- 细胞还原性手术 (CRS) 与高热性腹腔内化疗 (HIPEC) 是癌症治疗的标准.
- 隔膜切除 (DR) 和胸内HIPEC (HITAC) 可能是必要的,以实现完全的细胞减小 (CC-0).
研究的目的:
- 详细说明结合腹部和胸内HIPEC (HITAC) 的技术.
- 报告手术后的过程,发病率和这种联合手术的长期结果.
主要方法:
- 一个单心数据库的回顾性分析确定了七名接受同步HITAC的患者.
- 收集的数据包括手术细节,化疗剂,术后恢复,并发症和随访.
主要成果:
- 七名患者接受了部分隔膜切除的HITAC.
- 平均手术时间为580分钟;术后4小时内或在第1天内发生了输出管.
- 术后并发症是最小的,有1名患者出现了胰腺和肺炎;没有观察到多叶膜复发,随访时间中位数为88个月.
结论:
- 结合HIPEC和胸内化疗 (HITAC) 是一个可行的和安全的程序.
- 在术后预计会出现显著的胸部排水.
- 可实现有利的长期结果,特别是在患有低度腹间皮质瘤的患者中.
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