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Updated: May 11, 2025

A Rapid In Vivo Bioassay for Developmentally Active Enhancers
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USP11/TCEAL1复合体促进了转录延长,以维持神经母细胞瘤中的瘤基因表达

Markus Dehmer1,2, Katrin Trunk1, Peter Gallant1

  • 1Theodor Boveri Institute, Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, 97074 Würzburg, Germany.

Genes & development
|April 18, 2025
PubMed
概括

双化酶USP11和TCEAL1蛋白质复合体通过保护TCEAL1免受降解来促进转录延长. 这个复合体支持瘤基因表达在介质瘤中,可能有助于治疗逃脱.

关键词:
这就是MYCNCN.的RNA聚合酶II.在TCEAL1中.这是一个很好的例子. TFIISUSP11 美国 美国转录延长 延长 转录延长

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