便calprotectin的升高:囊内镜是否在诊断算法中发挥作用?
S Vibhishanan1, P Oka1, S Zammit2
1Unidad Académica de Gastroenterología, Hospitales Educativos de Sheffield, Sheffield, United Kingdom; División de Medicina Clínica, Facultad de Medicina y Salud Poblacional, Universidad de Sheffield, Sheffield, United Kingdom.
Revista de gastroenterologia de Mexico (English)
|April 18, 2025
概括
小肠囊内镜 (SBCE) 在患有便calprotectin升高和正常结肠镜的患者早期诊断小肠克罗恩病 (SBCD) 中具有价值. 对于SBCD,SBCE提供了比MRE更高的诊断产量.
科学领域:
- 胃肠病学 胃肠病学
- 诊断成像 诊断成像 诊断成像
- 炎症性肠道疾病研究研究
背景情况:
- 在正常结肠镜检查中便calprotectin (FC) 的升高表明潜在的小肠病理.
- 小肠囊内镜 (SBCE) 是检查小肠的一个关键工具.
研究的目的:
- 评估SBCE在患有高FC和正常结肠镜的患者中的实用性.
- 为了比较SBCE的诊断产量与磁共振肠道学 (MRE).
主要方法:
- 对320名患有高FC和正常结肠镜检查的患者进行了回顾性分析,这些患者接受了SBCE.
- 患者被分为三个组:孤立的小肠克罗恩病 (SBCD),正常SBCE的升高FC,和孤立的终端乳头炎.
主要成果:
- 在52.4%的患者中,SBCE新诊断的SBCD.
- 与MRE相比,SBCE显示SBCD的诊断产量显著更高 (p < 0.0001).
- 在正常SBCE的患者中,诊断包括H. pylori,NSAID使用,腹腔疾病和微观结肠炎.
结论:
- 即使在正常发现的情况下,SBCE也会显著影响患者管理.
- 在检测早期SBCD方面,SBCE优于MRE.
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