身体多病症与老年双极性障碍 (OABD) 患者的认知表现没有独立的关联
Alexandra J M Beunders1, Nicole C M Korten2, Mariska Bot3
1GGZ inGeest Specialized Mental Health Care, Amsterdam, the Netherlands; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam, the Netherlands; Amsterdam Public Health, Mental Health program, Amsterdam, the Netherlands.
International psychogeriatrics
|April 18, 2025
概括
身体多病症并没有独立地与老年双相情感障碍 (BD) 的认知衰退有关. 人口统计和生活方式等共同因素可能会影响这两种情况,而不是直接的因果关系.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 老年学是一门学科.
背景情况:
- 认知障碍在双相情感障碍 (BD) 中普遍存在,特别是在老年人 (≥50岁).
- 老年双相情感障碍 (OABD) 认知缺陷的具体原因尚不清楚.
- 在OABD中调查身体健康和认知之间的关系至关重要.
研究的目的:
- 检查OABD患者的身体多病症和认知表现之间的关联.
- 在身体健康方面区分主观和客观认知功能.
- 为了确定这群人群中可能导致认知障碍的潜在因素.
主要方法:
- 一项对来自荷兰老年双极症 (DOBi) 队列的170名患有BD的门诊患者≥50岁的横截面研究.
- 通过结构化面试评估身体疾病;用神经心理测试 (客观) 和认知失败问卷 (CFQ) (主观) 测量认知功能.
- 对人口统计,生活方式和精神病变量进行调整的线性回归分析.
主要成果:
- 最初的分析显示,多病症和较低的复合认知分数之间存在显著的关联,但在完全调整后,这种关联消失了.
- 多种疾病与更差的执行功能有关,但这一发现在调整后也失去了统计学意义.
- 在多病症和主观认知功能 (CFQ分数) 之间没有发现显著的独立关联.
结论:
- 身体多病症似乎不是一个独立的预测者较差的认知或主观功能在老年人患有双相情感障碍.
- 共同的风险因素,包括人口统计,精神病特征和生活方式,可能同时导致OABD的身体疾病和认知缺陷.
- 需要进一步的研究来阐明影响OABD认知的因素的复杂相互作用.
更多相关视频
10:13Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
13.6K
09:01A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
Published on: May 7, 2014
10.1K
相关概念视频
01:30Bipolar Disorder
30
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
30
01:30Negative and Cognitive Symptoms of Schizophrenia
34
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
34
01:30Cognitive Development During Adulthood
23
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
23
01:24Mania and Antimanic Drugs: Overview
101
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
101
01:27Language and Cognition
291
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
291
01:30Bulimia Nervosa
33
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
33