绕过延迟:通过炎症标志物评估将儿科内肠接病例引导到手术室
Mahmoud Elhadidi1,2, Mohamed Elghazaly1,2, Adham W El-Saied1,2
1Department of Pediatric Surgery, Mansoura University, Mansoura, Egypt.
World journal of surgery
|April 19, 2025
概括
血清蛋白与白蛋白的比率 (CAR) 和淋巴细胞与血清蛋白的比率 (LCR) 能够有效地预测肠道内中肠道缩的发生. 升高的CAR和低的LCR表明需要进行肠切除手术的可能性更高.
科学领域:
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
- 生物标志物发现发现
背景情况:
- 肠道亡是肠接的一个严重并发症.
- 系统性炎症标志物,包括CAR和LCR等比率,被探索为炎症状况的预测因素.
研究的目的:
- 评估炎症标志物 (NLR,PLR,LCR,CAR) 在预测肠道缩和肠切患者切除的必要性方面的有效性.
- 为了确定哪些炎症标志物组合最好地与肠道死的手术内发现相关.
主要方法:
- 对100名需要手术的静脉注射患者进行了回顾性队列研究.
- 患者根据肠道切除被分成几组.
- 对炎症标志物比率 (NLR,PLR,LCR,CAR) 的分析及其与手术结果的相关性.
主要成果:
- 在切除组 (15.27) 与非切除组 (3.56) 中,CRP与白蛋白比率 (CAR) 的平均值显著更高.
- 切除组 (0.116) 与非切除组 (0.509) 的平均淋巴细胞与CRP比率 (LCR) 显著降低.
- 在预测切除需要时,ROC分析显示LCR (切除值0.1233,灵敏度85.7%,特异性90%) 和CAR (切除值7.73,灵敏度92.6%,特异性90%) 的AUC非常好. 如果CAR增加1个单位,则切除风险增加1.42.
结论:
- 卡尔是统计学上显著的预测器,需要肠切除的肠道切除.
- LCR提供了有价值的信息,应该与CAR一起用于外科决策.
- 使用CAR (截止值7.73) 和LCR (截止值0.1233) 可以帮助优先考虑患者,避免延迟,并改善结果.
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