基于电子健康记录的招聘支持系统:一个范围审查,以改善患者在临床试验中的纳入
Morgan Vaterkowski1, Christel Daniel2, Ambre La Rosa3
1Sorbonne Université, INSERM, Université Sorbonne Paris-Nord, Laboratoire d'informatique médicale et d'ingénierie des connaissances en e-santé, LIMICS, 75006 Paris, France; Clinical Science and Operations, Sanofi Research and Development, Gentilly, France.
International journal of medical informatics
|April 19, 2025
概括
电子健康记录 (EHR) 系统可以帮助临床试验招聘. 然而,大多数当前的系统都是以试验为中心的,患者数据集成和回顾性评估有限,突出需要改进系统设计和协调影响评估.
科学领域:
- 生物医学信息学 生物医学信息学
- 临床试验管理 临床试验管理
- 医疗保健服务研究 医疗服务研究
背景情况:
- 电子健康记录 (EHR) 越来越多地用于临床试验 (CT) 患者招募.
- 评估基于EHR的临床试验招聘支持系统 (CTRSS) 对于优化试验效率至关重要.
研究的目的:
- 对评估基于EHR的CTRSS的文章进行范围审查.
- 综合系统集成,技术方面和评估方法的发现.
主要方法:
- 搜索了3个生物医学文献数据库 (2013-2024) 使用关键字:"临床试验"",患者招募"和"EHR".
- 包括评估基于EHR的CTRSS的文章,由多个审稿人进行抽象和全文选.
- 数据的提取和合成重点是临床工作流的整合,技术方面和评估方法.
主要成果:
- 44篇文章评估了基于EHR的CTRSS在不同的环境中.
- 75%的系统以试验为中心;只有20%在相关临床时间点提供了资格信息.
- 在32%的研究中发生了电子健康记录数据的转换,在48%的研究中发生了计算机辅助的资格标准转换.
- 患者试验匹配主要使用结构化数据 (55%);61%的评估是回顾性.
结论:
- 新兴指标评估基于EHR的CTRSS在用户,技术和社会层面.
- 需要进一步的研究来提高EHR数据和资格标准的质量和可计算性.
- 需要进行统一的评估,以证明基于EHR的CTRSS对招聘率,延迟和成本的影响.
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