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老鼠衍生的支气管上皮细胞通过MBD2-sICOSL轴调节喘中的Th17细胞分化

Zhifeng Chen1, Yulin Shang2, Yu Yuan1

  • 1Department of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan 410011, China.

Cellular immunology
|April 19, 2025
PubMed
概括

来自老老小鼠的支气管上皮细胞 (BEC) 通过MBD2-sICOSL信号促进Th17细胞的分化,与年轻小鼠的细胞不同,Th2细胞更受青. 这突显了老年喘发病的关键途径.

关键词:
喘 喘 是一种支气管上皮细胞是支气管上皮细胞.MBD2 MBD2 的意思是什么?Th17细胞的细胞.sICOSL 的使用.

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