前庭刺激是否会改变昼夜节律和睡眠? 一个系统的审查
Melvin Galin1, Emma Milot2, Tristan Martin3
1Université de Caen Normandie, Inserm, EPHE-PSL, PSL University, CHU de Caen, GIP Cyceron, U1077, NIMH, 14000, Caen, France; Le Mans Université, Movement - Interactions - Performance, MIP, 72085, France.
Sleep medicine
|April 19, 2025
概括
静止体刺激显示出改善昼夜节律和睡眠质量的前景. 这次审查评估了其影响,在分析的大多数研究中发现对睡眠有有益影响.
科学领域:
- 神经科学是一个神经科学.
- 时间生物学 时间生物学
- 睡眠科学 睡眠科学
背景情况:
- 循环节律和睡眠对人类健康至关重要,干扰会对健康产生负面影响.
- 前置系统与昼夜和睡眠调节中心共享路径,这表明存在潜在的联系.
- 静脉刺激正在被探索为治疗睡眠和昼夜干扰的非药物干预.
研究的目的:
- 系统地审查和评估各种前体刺激技术对人类昼夜节律和睡眠模式的影响.
- 评估前体刺激在缓解睡眠和昼夜过程中障碍的有效性.
主要方法:
- 一个遵循PRISMA指南的系统审查,在PROSPERO注册 (CRD42024492913).
- 在PubMed和ScienceDirect数据库中搜索1950年至2023年间发表的文章,更新至2024年1月.
- 包括来自96篇选文章的12项研究,并评估偏见风险.
主要成果:
- 静止体刺激对昼夜节律有显著的有益影响.
- 在11项研究中,有8项报告说前体刺激对睡眠质量和调节的积极影响.
- 偏差风险评估表明,七项研究的偏差风险较低,而五项研究对偏差风险存在中度至高的担忧.
结论:
- 静脉口腔刺激成为一种潜在有效和有前途的非侵入性方法,可以增强昼夜节律的调节.
- 这些发现表明,前体刺激可以积极影响睡眠,这需要进一步的研究和临床应用.
- 需要进一步进行高质量的研究,以巩固前体刺激在睡眠和昼夜调节障碍中的治疗作用.
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