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杂交影响了丹麦泽西和霍尔斯坦乳牛的生存

S Tenhunen¹, J R Thomasen², L P Sørensen²

¹Centre for Quantitative Genetics and Genomics, Aarhus University, 8000 Aarhus, Denmark; VikingGenetics, 8960 Randers SØ, Denmark.

Journal of dairy science

|April 19, 2025

概括

丹麦的泽西奶牛比丹麦的霍尔斯坦奶牛的生存率更高,因为近亲繁殖率较低. 管理基因组内生育,特别是长期的同胞性,对于奶牛的生存和可持续性至关重要.

科学领域:

动物科学动物科学
乳牛遗传学乳牛遗传学
生殖生物学生殖生物学

背景情况:

亲生繁殖可能会对动物健康和生产力产生负面影响.
基因组内生育,以同卵性 (ROH) 的运行来衡量,提供了比血统内生育更精确的评估.
了解近亲繁殖的影响对于可持续的奶牛养殖至关重要.

研究的目的:

评估血统和基因组内生育对丹麦泽西和荷尔斯坦乳牛生存的影响.
为了比较两种品种之间的生存率和相关风险.
为了研究不同长度的ROH对奶牛生存的影响.

主要方法:

使用Kaplan-Meier分析和Cox比例危险模型来估计生存概率和危险风险.
用不同长度的同胞性 (ROH) 运行来量化基因组内生殖.
此外,还计算和比较了血统内生系数.

主要成果:

丹麦的泽西奶牛比丹麦的荷尔斯坦奶牛的生存概率更高 (1.3-4%更高) 和危险风险更低 (22-29%更低).
基因组 (F_roh) 和血统近亲繁殖都增加了1%的危险风险,每增加1%的近亲繁殖.
较长的ROH段 (>10 Mb) 增加了危险风险,而较短的段 (1-2 Mb) 降低了危险风险.

结论:

管理基因组内生育对于减轻杀风险和提高奶牛生存率至关重要.
避免密切的近亲繁殖 (ROH>5 Mb) 和在繁殖计划中利用基因组关系可以提高乳制品系统的可持续性.
繁殖值与生存概率有积极的相关性,突出了它们在选择中的重要性.

关键词:

危险的风险危险的风险亲生繁殖是一种繁殖方式.一系列的同卵性性.幸存的可能性生存的可能性.

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