基于血液的结肠直肠癌查:在2个阿巴拉契亚州的初级保健诊所实施
William B Haynes1, Mridula P Talari2, Karen A Elmore1
1Johnston Memorial Hospital Residency Program, Ballad Health, Johnson City, Tennessee.
American journal of preventive medicine
|April 19, 2025
概括
提供基于血液的测试显著增加了结直肠癌查率,并在初级保健诊所比标准方法更优先. 这项创新有望改善风险人群的癌症检测.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 结肠直肠癌 (CRC) 是全球和美国癌症死亡的主要原因.
- 与美国其他地区相比,阿巴拉契亚地区的CRC查率较低,发病率/死亡率较高.
- 解决CRC查方面的差异是一个关键的公共卫生目标.
研究的目的:
- 评估提供基于血液的查测试对CRC查率的影响.
- 为了确定基于血液的测试是否与标准选项相比是首选的查方法.
- 评估新型查方法在服务不足的人群中的有效性.
主要方法:
- 在两个初级保健诊所进行了一项比较研究,分两个三个月的阶段进行.
- 第1阶段使用标准护理CRC查选项 (n=74).
- 第二阶段在标准选项 (n=165) 之外引入了基于血液的测试,数据将在2024年收集和分析.
主要成果:
- 总体而言,完成的CRC查率从第一阶段 (n=33) 到第二阶段 (n=151) 显著增加.
- 在第二阶段,基于血液的测试被高度优先于标准护理选择 (134对29名参与者).
- 引入基于血液的测试证明了对查参与有实质性的积极影响.
结论:
- 作为常规查选项提供的基于血液的测试显著改善了CRC查率.
- 患者的偏好强烈支持基于血液的测试,而不是传统的查方法.
- 这种方法显示了提高CRC查遵守率和平均风险成年人的结果的潜力.
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