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从Ganoderma lucidum和Ganoderma neo-japonicum中提取的多糖化合物的模拟肠道微生物发酵

Francis Ayimbila¹, Varaporn Chaiyama², Supatcharee Siriwong³

¹Specialized Research Units: Prebiotics and Probiotics for Health, Department of Biotechnology, Faculty of Agro-Industry, Kasetsart University, Bangkok 10900, Thailand; Center for Advanced Studies for Agriculture and Food, KU Institute of Advanced Studies, Kasetsart University (CASAF, NRU-KU), Bangkok 10900, Thailand.

International journal of biological macromolecules

|April 19, 2025

概括

热水提取物从甘菌,包括甘光和甘新日,积极调节肠道微生物群. 这两种提取物都促进有益的细菌并增加短链脂肪酸,而Ganoderma lucidum显示出更明显的效果.

科学领域:

菌类学菌类学是指菌类学.
微生物学微生物学
生物化学生物化学

背景情况:

药用如Ganoderma lucidum被广泛研究其健康益处.
新日 (Ganoderma neo-japonicum) 是一种较少探索的物种,具有潜在的治疗特性.

研究的目的:

为了比较热水提取物的化学成分,从光 lucidum (GL) 和光新日 (GN).
研究这些提取物对肠道微生物群组成和功能的影响.
评估G. neo-japonicum作为肠道微生物群调节者的潜力.

主要方法:

热水提取甘菌物种的热水提取.
提取物的化学分析,专注于多糖和含量.
用肠道细菌进行体外发酵实验.
微生物群落变化和短链脂肪酸 (SCFA) 生产的分析.

主要成果:

无论是GL还是GN的提取物都含有可比的多糖度,但GL的总含量更高.
微生物群分析显示,使用两种提取物时,有益细菌 (例如Prevotellaceae,Bifidobacteriaceae) 的增加和Enterobacteriaceae的减少.
增强了SCFA (酸,酸,黄油酸) 的产生,GL显示出更强的效果.
在GL中确定了特定的葡萄皮酶结构,但在GN中没有.

结论:

来自两种Ganoderma物种的热水提取物有益地调节肠道微生物群并增加SCFA的产生.
甘 lucidum 提取物对微生物群调节表现出更显著的作用.
新日 (Ganoderma neo-japonicum) 显示出作为肠道微生物群调节器的潜力,需要进一步调查.

关键词:

生物活性特征生物活性特征甘类甘类我们的肠道微生物群.热水提取物热水提取物短链脂肪酸短链脂肪酸

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