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Updated: Jul 6, 2026

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合理设计GH11西兰酶以平衡活动稳定性权衡

Zhihong Li1, Xiang Li1, YiYi Zhou1

  • 1School of Biological Science, Jining Medical University, Rizhao 276827, China.

International journal of biological macromolecules
|April 19, 2025
PubMed
概括

酶工程面临着稳定性-活性权衡. 这项研究增强了GH11西兰酶XynIIII.

关键词:
分子动力学模拟的模拟.理性的设计理性的设计.结构分析 结构分析在X射线晶体学.在Xylanase的使用中.

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Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...