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Updated: May 10, 2025

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
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怀孕和疾病中的宫功能:单细胞分析的新见解

ShanmugaPriyaa Madhukaran1, Yevgenia Y Fomina2, Mala Mahendroo1

  • 1Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX; Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX.

American journal of obstetrics and gynecology
|April 19, 2025
PubMed
概括

单细胞转录学揭示了宫细胞的可塑性和独特的免疫反应,进步了对生育,怀孕和宫癌的理解. 这些见解为新的疾病生物标志物和疗法铺平了道路.

关键词:
宫癌:子宫癌是一种癌症.宫部的发育 宫部的发展宫的可塑性 宫的可塑性宫重塑是指宫的重塑.宫的子宫可以玻璃杯细胞 玻璃杯细胞炎症介导的早产 过早分娩甲基形成的过程中.宫粘膜免疫的宫免疫.怀孕 怀孕 怀孕 怀孕 怀孕这就是scRNA-seqq.

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Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
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