长期食用大豆食纤维饮食改变了肠道内部环境:专注于慢性性结肠炎
Yi Wang1, Ruining Zhang1, Mingzhe Li1
1College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, China; Soybean Research & Development Centre, Division of Soybean Processing, Chinese Agricultural Research System, Changchun 130118, China.
Food research international (Ottawa, Ont.)
|April 19, 2025
概括
高纯度大豆分离食纤维 (HPSIDF) 来自瓜通过减少炎症和促进有益细菌有益于肠道健康. 这一发现为花的利用和性结肠炎的管理提供了可持续的解决方案.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 生物技术是生物技术.
背景情况:
- 作为大豆加工副产品的奥卡拉带来了环境挑战和资源浪费.
- 富含不溶性食纤维的大豆残留物显示出对性结肠炎的潜在益处.
- 慢性性结肠炎 (CUC) 涉及显著的肠损伤和炎症.
研究的目的:
- 为了研究长期高纯度大豆隔离食纤维 (HPSIDF) 消费对肠道健康的影响.
- 为了确定HPSIDF是否促进有益的肠道细菌和代谢物.
- 评估HPSIDF在缓解CUC诱导的肠损伤方面的潜力.
主要方法:
- 慢性性结肠炎 (CUC) 在小鼠中被诱导使用2%的硫酸 (DSS).
- 一项为期九周的干预研究涉及长期的HPSIDF消费.
- 分析包括炎症因子水平,肠道组织损伤和肠道微生物群组成.
主要成果:
- 在小鼠中,长期使用HPSIDF调节了炎症因素,并减少了肠道组织损伤.
- 摄入 HPSIDF 促进了 Oscillospira 的扩散,并抑制了 Lactobacillus intestinalis 的降解.
- 有益的代谢物,包括Agmatine和Betaine增加,支持肠道菌群和内部环境的改善.
结论:
- 长期摄入HPSIDF会积极调节肠道特性,促进有益的肠道菌群和代谢物.
- HPSIDF显示出作为慢性性结肠炎治疗剂的潜力.
- 这项研究提供了一种高价值的花利用策略,将废弃产品转化为促进健康的成分.
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