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Poonam Joshi¹, Labani Kole¹, Asawari Patil¹

¹Advanced Centre for Treatment, Research, and Education in Cancer, Tata Memorial Centre, Mumbai, India.

Oral surgery, oral medicine, oral pathology and oral radiology

|April 19, 2025

概括

唇状细胞癌 (SCC) 的结果取决于瘤的位置和阶段. 退休性SCC和高级阶段的预后较差,需要量身定制的治疗来改善存活率.

科学领域:

在瘤学瘤学.
皮肤病学皮肤病学
头部和部手术头部和部手术

背景情况:

唇状细胞癌 (SCC) 是一种常见的恶性瘤.
影响唇部SCC存活率的预后因素需要进一步阐明.
了解子站点特定的行为对于治疗规划至关重要.

研究的目的:

评估唇部SCC的治疗结果.
为了确定唇部SCC患者的生存预测因素.
根据瘤亚部位,阶段和差异化分析预后差异.

主要方法:

在印度第三级癌症中心对294例唇部SCC病例 (2012-2022) 的回顾性分析.
对患者人口统计,瘤特征,治疗和生存数据的分析.
回归和卡普兰-梅尔分析,以评估生存预测因素和亚站点特定结果.

主要成果:

下唇SCC是最常见的 (58.7%),其次是 commissure (22.4%) 和上唇 (14.3%).
晚期瘤 (T4A) 和委托性SCC表现出明显较差的结果 (P = .02).
上唇SCC的存活率最好 (平均:31.02个月),而小唇SCC的存活率最差 (平均23.46个月). 多模式治疗改善了结果.

结论:

瘤亚部位和阶段是唇部SCC存活率的关键决定因素.
针对性治疗策略对于诸如唇部部位等高风险的子部位至关重要.
优化预后需要解决唇部SCC子站点之间的预后差异.

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