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Updated: May 10, 2025

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BiP和Grp94的结构和功能动态:治疗发现的机会

Ikponwmosa Obaseki1, Chioma C Ndolo1, Ayodeji A Adedeji1

  • 1Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA.

Trends in pharmacological sciences
|April 19, 2025
PubMed
概括

结合性免疫球蛋白 (BiP) 和调节葡萄糖的蛋白质94 (Grp94) 是关键的ER陪伴者. 针对它们的结构变化的新测试和化合物提供了治疗潜力,用于药物发现的机器学习加速了这种治疗潜力.

关键词:
这就是BiP BiP BiP.在Grp94中使用.药物设计 药物设计细胞内膜网膜的压力应激分子的陪伴者是分子的陪伴者.

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