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植物性饮食指数与乳腺癌风险之间的关联:一个病例控制研究
Fateme Souni1, Fatemeh Mansouri1, Fatemeh Jafari2
1Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Journal of health, population, and nutrition
|April 19, 2025
概括
健康的植物性饮食可能会降低伊朗女性,特别是绝经后女性的乳腺癌风险. 不健康的植物性饮食与绝经前妇女乳腺癌发生率增加有关.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 关于植物性饮食和乳腺癌 (BrC) 风险,存在相互矛盾的证据.
- 本研究通过评估伊朗妇女的植物性饮食指数 (PDI,hPDI,UPDI) 和BrC几率来解决这些不一致的问题.
研究的目的:
- 调查坚持植物性饮食 (健康和不健康) 与伊朗妇女患乳腺癌的风险之间的关联.
主要方法:
- 一项病例控制研究涉及133名患有BrC的伊朗妇女和265名来自德黑兰医院的对照.
- 植物性饮食指数 (PDI,hPDI,UPDI) 基于18个食物组进行计算.
- 使用后勤回归分析来评估PDI和BRC几率之间的关系.
主要成果:
- 对健康植物性饮食 (hPDI) 的更高坚持与降低BrC几率 (OR=0.495) 有关.
- 绝经后女性的hPDI较高,BrC几率明显较低 (OR=0.342对于T2,OR=0.262对于T3).
- 绝经前妇女更坚持不健康的植物性饮食 (uPDI) 增加了BRC几率 (OR=2.546).
结论:
- 一种健康的植物性饮食模式,富含蔬菜,水果,全谷物,坚果和豆类,似乎对BrC有保护作用,特别是在绝经后的妇女中.
- 建议进行进一步的前性研究来证实这些发现,考虑到更年期状态和BrC亚型.
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