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Updated: May 12, 2025

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SARS-CoV-2 NSP2 特别与细胞蛋白 SmgGDS 相互作用

Xiaoyu Chu1, Yixuan Yang1, Hangtian Guo1

  • 1The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Institute of Viruses and Infectious Diseases, Chemistry and Biomedicine Innovation Center (ChemBIC), ChemBioMed Interdisciplinary Research Center, Institute of Artificial Intelligence Biomedicine, Nanjing University, Nanjing, China.

Biochemical and biophysical research communications
|April 20, 2025
PubMed
概括

SARS-CoV-2非结构蛋白2 (NSP2) 独特地结合小G蛋白解离刺激剂 (SmgGDS),抑制其关氨酸核酸交换因子活性. 这种相互作用扰乱了RhoA信号传输,可能导致COVID-19的发病.

关键词:
在NSP2中,NSP2是指NSP2中的NSP2.在RhoAAA这就是SARS-CoV-2病毒.在 SmgGDSDS 中.

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