对不同母亲年龄组怀孕风险的比较研究
Amala Sunder1, Yusuf Khaled Hadi1, Noor Ammar Alkhuzaei1
1From the Department of Obstetrics & Gynecology (Sunder, Bushaqer, Al khalifa,Darwish), Bahrain Defense Force Hospital, Riffa, Bahrain; (Hadi, Alkhuzaei), Royal College of Surgeons in Ireland, Busaiteen, and (Dayoub), Assisted Reproductive and Gynecology Centre, London.
Saudi medical journal
|April 20, 2025
概括
母亲年龄对怀孕结果产生重大影响. 年轻的母亲面临着早产和子宫内生长限制的更高风险,而年长的母亲则有更高的妊娠糖尿病发病率.
科学领域:
- 产科和妇科 产科和妇科
- 生殖健康 生殖健康
- 围产儿医学 围产儿医学
背景情况:
- 母亲年龄越来越被认为是影响怀孕结果的关键因素.
- 了解与不同孕产妇年龄组相关的特定风险对于优化产前护理和改善孕产妇和新生儿健康至关重要.
- 以前的研究表明,晚年母亲与某些妊娠并发症之间存在关联,但需要在不同年龄层进行全面的比较.
研究的目的:
- 评估和比较不同孕妇年龄组妊娠并发症的发生率.
- 为了确定与年轻 (<25岁) 和年长 (≥35岁) 母亲年龄相关的特定不良结果.
- 提供数据,可以为临床实践和与孕产妇年龄和怀孕风险相关的公共卫生策略提供信息.
主要方法:
- 在巴林国防军医院进行了对单子妊娠结果的回顾性分析.
- 研究人口 (n=2,972) 被分为四个年龄组:<25,25-29,30-34和≥35岁.
- 使用单变量逻辑回归来分析孕产妇和新生儿结局,调整相关孕产妇因素,统计显著性设置为p<0.05.
主要成果:
- 观察到母亲年龄和身体质量指数 (BMI),妊娠期糖尿病 (GDM) 和子宫内生长限制 (IUGR) 等结果之间存在显著的关联.
- 年龄≥35岁的女性的GDM发病率较高 (11.5%),相比于年龄<25岁的女性 (6.6%,p=0.027).
- 年轻女性 (25岁以下) 的IUGR (p=0.041) 和早产 (OR: 1.365,CI: 1.015-1.837) 的患病率较高.
结论:
- 母亲年龄是妊娠不良结果的独立风险因素.
- 较年轻的母亲年龄 (<25岁) 与早产和IUGR的风险增加有关.
- 先进的母亲年龄 (≥35岁) 与更高的GDM发病率有关.
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