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Updated: May 10, 2025

In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes
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在位直接神经重编程:现有方法及其优化.

Nikita V Dokukin1, Daria A Chudakova1,2, Matvey O Shkap1

  • 1Federal Center for Brain and Neurotechnology, Federal Medical and Biological Agency of Russia, Moscow, 117513, Russia.

Biochemistry. Biokhimiia
|April 20, 2025
PubMed
概括

直接将质细胞重新编程为神经元,为中枢神经系统 (CNS) 修复提供了一个有前途的治疗策略. 这种方法绕过多能性,将现有的质细胞转化为功能神经元,用于治疗神经退行性疾病.

关键词:
星球细胞是星球细胞.直接重新编程是直接的重编程.效率 效率 效率 效率 效率 效率 效率神经元神经元的神经元复兴再生是一种再生方式.转录因子是一种转录因子.

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