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在急性和慢性心力衰竭中,左心房应变的预后值:元分析

Maria Concetta Pastore¹, Mariangela Vigna¹, Andrea Saglietto²

¹Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.

ESC heart failure

|April 21, 2025

概括

高峰心房纵向应变 (PALS) 有效地预测心力衰竭 (HF) 的结果. 较低的PALS表明死亡率和住院的风险更高,有助于患者风险分层.

科学领域:

心脏病学心脏病学
医疗成像医学成像
预测预测预测预测预测

背景情况:

心力衰竭 (HF) 是一个重要的全球健康挑战,具有复杂的预后评估.
斑点跟踪左心房应变因其在HF结果中的预测能力而得到认可.

研究的目的:

在急性和慢性心力衰竭中系统地评估心房纵向应变 (PALS) 峰值的预后意义.
分析PALS在不同左心室 (LV) 功能,年龄组和性别的预后价值.

主要方法:

在医疗数据库中进行了遵循PRISMA原则的系统文献搜索.
八项研究的元分析 (n=5767) 涉及减少,轻度减少和保存喷射分数 (EF) 和≥6个月随访的患者.
主要终点包括全因死亡率和HF住院,使用随机效应元分析进行分析.

主要成果:

全球PALS的下降独立地与主要终点 (HR=1.05;P<0.01) 的5%增加有关.
亚组分析显示,急性和慢性HF之间的预后值没有显著差异.
超回归表明PALS的预后值在患有左下心室喷射分数 (LVEF) 的患者中更强.

结论:

全球PALS作为急性和慢性心力衰竭的宝贵预后工具.
对风险分层来说,PALS提供了额外的独立价值,特别是在LVEF降低的患者中.
这一指标可以通过提高HF患者风险评估的准确性来增强临床实践.

关键词:

严重急性严重急性年代记年代记年代记年代记心脏衰竭是因为心脏衰竭.左心房应变是左心房应变.预测预后预测预测斑点跟踪跟踪斑点跟踪跟踪

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