硫酸盐和牙周炎之间的J形关联:来自NHANES 2009-2014年的横截面研究
Pengfei Liu1, Huan Zhou2,3, Tingting Wang4
1Ningbo Institute of Innovation for Combined Medicine and Engineering, The Affiliated Lihuili Hospital of Ningbo University, Ningbo, China.
Journal of periodontology
|April 21, 2025
概括
在美国成年人中,氨酸暴露显示了复杂的J形链接与牙周炎风险. 低水平和高水平都可能增加风险,凸显了对牙健康的最佳硫酸酸盐平衡的需求.
科学领域:
- 口腔健康研究研究 口腔健康研究
- 毒理学 毒理学 毒理学
- 营养科学 营养科学
背景情况:
- 硫酸酸盐存在于环境和饮食来源中,具有潜在的健康影响.
- 它与美国成年人牙周炎风险的具体关联尚不清楚.
- 了解这种关系对于公共卫生和预防策略至关重要.
研究的目的:
- 评估硫酸暴露与牙周炎风险之间的关联.
- 通过使用大型,具有全国代表性的数据集来调查剂量-反应关系.
- 确定酸对牙周健康的有害影响的潜在值.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (2009-2014) 的横截面研究.
- 牙周炎使用2017年分类方案进行分类.
- 进行了受限立方线和加权多变量逻辑回归分析.
主要成果:
- 观察到,在硫酸氨酸暴露和牙周炎风险之间存在J型关联.
- 在3.32确定了一个转折点.
- 在较低和较高的暴露水平上都注意到风险增加,特别是在非肥胖和非高血压个体中.
结论:
- 在硫酸暴露和牙周炎之间存在复杂的J形关系.
- 缺乏和过度暴露于硫酸酸盐可能会增加牙周炎的风险.
- 需要进一步的前性研究来证实这些发现并阐明机制.
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