诊断高血压后第一个月的治疗改善了血压控制
Robert B Barrett1, Benjamin Riesser1, Benjamin Martin2
1Improving Health Outcomes, American Medical Association, Greenville, SC (R.B.B., B.R., S.E.S., B.M.E.).
Hypertension (Dallas, Tex. : 1979)
|April 21, 2025
概括
在诊断后的第一个月内开始抗高血压治疗,可以改善高血压患者的血压控制. 早期治疗是改善心血管结果的关键.
科学领域:
- 心脏病学 心脏病学
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 在诊断后6个月内控制高血压与较少的心血管事件有关.
- 在这个初始控制期间,患者经常被排除在指标之外.
- 早期开始治疗 (TI) 的时间影响了长期的血压 (BP) 管理.
研究的目的:
- 为了比较6到42个月的BP控制率.
- 评估在诊断后的第一个月内开始抗高血压治疗 (单一疗法) 的影响,而不是之后.
- 为了评估血压控制,无论后续的药物改变.
主要方法:
- 对15422名新诊断的未经治疗的高血压成年人的回顾性队列研究.
- 评估血压控制 (<140/90 mm Hg) 和TI时间相对于诊断.
- 使用后勤和考克斯比例危险回归模型来分析TI几率和随着时间的推移控制BP.
主要成果:
- 在第一个月患有TI的患者在6个月 (57.7%对47.8%) 和30个月 (66.8%对62.2%) 后显著改善了血压控制.
- 30个月后,BP控制率变得相似.
- 早期TI与在诊断后的最初30个月内改善血压控制有关.
结论:
- 在诊断后的第一个月内开始抗高血压治疗,可改善高血压控制长达30个月.
- 这种早期控制与更好的临床结果和高血压指标的表现有关.
- 第一个月的单一治疗对30%以上的患者来说是不够的,这表明需要持续管理.
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