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ортодонтика治疗对口腔微生物群多样性和组成的影响:一项纵向研究

Mohammad Khursheed Alam^1,2,3, Mohammad Younis Hajeer⁴, M Alfaleh Muhanna Abdulrahim¹

¹Department of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka 72345, Saudi Arabia.

|April 21, 2025

概括

固定牙科治疗显著改变了口腔微生物群,减少了多样性和组成的变化. 在治疗期间,加强口腔卫生至关重要,以防止微生物失衡和潜在的口腔健康问题.

科学领域:

口腔微生物学口腔微生物学
牙科研究牙科研究
微生物组分析

背景情况:

口腔微生物组在保持口腔健康方面发挥着至关重要的作用.
固定式正牙器具可能会影响口腔微生物环境.

研究的目的:

研究固定牙科治疗对口腔微生物群多样性和组成的影响.
为了识别与正义牙科干预相关的特定微生物变化.

主要方法:

16S rRNA测序用于分析唾液和斑块样本.
60名参与者在基线,3个月和6个月收集了样本.
进行阿尔法和β多样性分析以评估微生物变化.

主要成果:

3个月后观察到α多样性的显著下降,在6个月后部分恢复.
贝塔多样性分析显示了微生物组成的显著变化 (p < 0.01).
关键的变化包括 *Streptococcus mutans* 的增加和 *Streptococcus sanguinis* 的减少.

结论:

固定的正牙治疗明显改变了口腔微生物组.
观察到的变化,包括 *S. mutans* 的增加,突显了改善口腔卫生实践的必要性.
在正治疗期间预防口腔失生症对于保持口腔健康至关重要.

关键词:

ортодонтическое 治疗 ортодонтическое 治疗多样性的多样性多样性的多样性固定设备固定设备固定设备纵向研究是一种纵向研究.微生物组成微生物组成口腔微生物组是口腔的微生物组.

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