身体圆度指数与老年人肉症之间的关联:基于人口的研究
Jing Lyu1,2, Zhiwu Liu3, Hengjiang Gong1,2
1The Department of General Practice, The First Hospital of Lanzhou University, Lanzhou, China.
Frontiers in public health
|April 21, 2025
概括
身体圆度指数 (BRI) 是老年人肉症风险的实际预测指标. 较高的BRI与 Sarcopenia 的可能性增加有关,提供了一个具有成本效益的诊断工具.
科学领域:
- 老年学是指老年学的学科.
- 营养科学 营养科学
- 生物识别信息 生物识别信息
背景情况:
- 肌肉质量和功能的下降,影响老龄化人口,增加跌倒和骨折的风险.
- 目前的麻症诊断方法 (CT,DXA) 是复杂而昂贵的,延迟了预防.
- 需要易于使用的工具来识别患有肉症风险的个体.
研究的目的:
- 为了研究身体圆度指数 (BRI) 与美国老年人肉症之间的关联.
- 为了确定BRI是否可以作为肉症风险的实际预测指标.
- 探索BRI在老龄化人口中识别肉症的实用性.
主要方法:
- 从国家健康和营养检查调查 (NHANES) 中对9,411名老年人的横截面研究.
- 权衡分析包括23,985,011名患有肉症的个人.
- 使用多变量逻辑回归和ROC曲线分析来评估BRI与肉症的关联.
主要成果:
- 患有肉类的个体的BRI平均值显著更高,并患有更多的并发症 (高血压,糖尿病).
- 每增加1个单位的BRI与64%更高的肉症风险相关 (OR = 1.64).
- BRI证明了对萨科佩尼亚诊断的强有力的预测能力 (AUC = 0.744).
结论:
- 升高的BRI与美国老年人肉症风险增加有关.
- BRI提供了一种实用的,具有成本效益的人类指数,用于预测肉症风险.
- BRI可能有助于及时识别和预防老年人群中的肉症.
相关概念视频
Bone Disorders
3.3K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.3K
Changes in the Appendicular Skeleton with Age
1.8K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
1.8K
The Effect of Aging on Tissues
2.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.0K


