糖尿病黄斑瘤患者的法化手术:在手术前或与手术同时进行静脉内抗VEGF疗法吗?
Yusuf Ziya Güven1, Mehmed Uğur Işık2, Serdar Ilgüy2
1Department of Ophthalmology, Izmir Katip Çelebi University Atatürk Educating and Research Hospital, Izmir 35200, Türkiye.
International journal of ophthalmology
|April 21, 2025
概括
在白内障手术前进行手术前的抗血管内皮生长因子 (VEGF) 治疗对于糖尿病黄斑 (DME) 比同时治疗更有效. 这种时间有助于防止术后斑点厚度的增加.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 血管生物学 血管生物学
背景情况:
- 糖尿病黄斑 (DME) 是糖尿病患者视力丧失的主要原因.
- 白内障手术可以加剧DME,导致斑点厚度增加.
- 抗血管内皮生长因子 (VEGF) 治疗是对DME的常见治疗方法.
研究的目的:
- 确定在接受白内障手术的DME患者中抗VEGF治疗的最佳时间.
- 为了比较手术前与与白内障手术同时进行的抗VEGF治疗的疗效.
主要方法:
- 一项涉及四组不同程度糖尿病视网膜病变和DME的患者的研究.
- 患者接受了与白内障手术同时或在白内障手术前一周接受抗VEGF治疗.
- 测量包括最佳校正的视敏度,眼内压,中央黄斑厚度 (CMT) 和多个时间点的平均黄斑厚度 (MMT).
主要成果:
- 在接受同时或不接受抗VEGF治疗的组中,白内障手术显著增加了CMT和MMT.
- 在接受手术前抗VEGF治疗的组中,没有观察到CMT或MMT的显著增加.
- 患有糖尿病视网膜病变但没有DME的组与没有糖尿病并发症的组相比,黄斑厚度的增加更大.
结论:
- 在DME患者中,手术前的抗VEGF治疗更有效地预防白内障手术后的黄斑加厚.
- 抗VEGF治疗的时间对于在白内障手术的背景下管理DME至关重要.
更多相关视频
08:10An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy
Published on: January 25, 2019
7.7K
10:24Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
10.0K
相关概念视频
Angle Closure Glaucoma: Treatment
374
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
374
Open Angle Glaucoma: Treatment
358
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
358
