结核病相关的运动障碍:系统范围审查强调地理差异,表型模式,治疗反应和全球报告中的知识差距
Soaham Desai1, Ravi Yadav2, Divyani Garg3
1Department of Neurology, Shree Krishna Hospital Pramukhswami Medical College, Bhaikaka University, Anand, India.
Movement disorders clinical practice
|April 21, 2025
概括
结核病相关的运动障碍 (TBRMDs) 是多种多样的,通常与特定的脑损伤位置有关. 早期诊断和多式疗法对于管理中枢神经系统结核病的神经学并发症至关重要.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 神经科学是一个神经科学.
背景情况:
- 中枢神经系统结核病 (CNS TB) 是一种严重的并发症.
- 运动障碍是中枢神经系统结核病的一个未被认可的表现.
- 关于结核病相关运动障碍 (TBRMDs) 的流行病学,病理生理学和管理,存在知识差距.
研究的目的:
- 综合有关TBRMDs的现有证据.
- 为了描述TBRMDs的频谱.
- 评估诊断方法,总结管理策略和结果.
主要方法:
- 根据PRISMA-ScR指南进行范围审查.
- 在PubMed,EMBASE和Scopus数据库中进行系统搜索.
- 数据提取,使用乔安娜·布里格斯研究所工具进行质量评估和主题综合.
主要成果:
- 分析了包括91例病例在内的36项研究.
- 最常见的疾病:震 (27.5%),胆发病 (26.4%),心肌缩 (16.5%).
- 现象学与病变位置相关 (例如,带有胆 ?? /肌的基底腺病变). 病原包括脑膜炎,结核瘤和血管炎. 治疗反应有所不同,43.9%的患者完全康复,32.9%的患者没有改善.
结论:
- TBRMDs呈现异质,受病变位置和病变发生因素的影响.
- 早期识别,神经成像和多式联络管理至关重要.
- 需要共识标准和前性研究,特别是在高负担地区,以改善护理和研究.
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