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Updated: May 10, 2025

A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training
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口服与延长释放注射纳尔特雷克松治疗酒精使用障碍住院患者:一项随机临床试验

Kara M Magane1, Kimberly A Dukes2, Sarah Fielman1

  • 1Department of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts.

JAMA internal medicine
|April 21, 2025
PubMed
概括

由于酒精使用障碍 (AUD) 在医院出院时开始服用口服或注射性纳尔德,在减少大量饮酒日和医疗保健使用方面表现出类似的有效性. 患者的偏好和保险应该指导治疗选择.

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CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
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