阐明因口疫病毒3C蛋白酶活性位点突变引起的结构动态

Sthitaprajna Sahoo1, Hak-Kyo Lee1,2, Donghyun Shin1

  • 1Department of Agricultural Convergence Technology, Jeonbuk National University, Jeonju, Republic of Korea.

PloS one
|April 21, 2025
PubMed
概括

使用分子动力学研究了口病病毒3C蛋白酶 (3Cpro) 突变C142S和C142L. C142S突变显示出显著的结构变化,影响了酶活性,并为新型抗病毒疗法提供了洞察力.

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