由M2巨细胞表达的TGF-β通过抑制中细胞干细胞TSG-6表达来促进伤口愈合

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Young Woo Eom1, Ju-Eun Hong2, Pil Young Jung3

  • 1Regeneration Medicine Research Center, Yonsei University Wonju College of Medicine, Wonju, Korea.

PloS one
|April 21, 2025
PubMed
概括

在伤口愈合过程中,M2巨细胞减少了由脂肪组织衍生干细胞 (ASC) 产生的瘤缩因子-α (TNF-α) 刺激的6基因 (TSG-6) 生产. 这一过程由转化生长因子-β (TGF-β) 介导,最终增强了伤口的修复.

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